Development and evaluation of an instant column connector for capillary gas chromatography
نویسندگان
چکیده
Coupling capillary columns in gas chromatography (GC) is not an operation that is only relevant for the users of the most advanced capillary GC methods. Simple single-column separations can also benefit from a properly selected and installed pre-column. Pre-columns connected upstream of the main column can increase the life-time of the column, efficiently refocus the analyte bands to result in better separations and can be used for more rugged on-column injection in medium-bore columns. Additionally coupling devices can also be used for other applications such as connecting two columns when a higher resolving power is needed, to connect columns of different stationary phase chemistries for optimising selectivity or to mend a broken column. Finally, column connectors are also needed for the more advanced applications of GC such as heart-cut twodimensional chromatography, comprehensive GCxGC or column back-flushing.
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